Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection.
نویسندگان
چکیده
In vitro minimum inhibitory concentrations were determined for 21 antimicrobials against 41 isolates of Mycoplasma mycoides subsp. mycoides small-colony type, the cause of contagious bovine pleuropneumonia. Of the antimicrobials used most widely in Africa, oxytetracycline and tilmicosin were effective, while the isolates were resistant to tylosin. These results provide a baseline for monitoring antimicrobial resistance.
منابع مشابه
Analysis of cellular responses to Mycoplasma mycoides subsp. mycoides small colony biotype associated with control of contagious bovine pleuropneumonia.
A better understanding of protective immune memory against contagious bovine pleuropneumonia (CBPP) is needed in order to facilitate the development of safer vaccines based on selected components of the pathogen. For this purpose, cells collected from lymph nodes draining the lungs of Mycoplasma mycoides subsp. mycoides small colony biotype (MmmSC)-infected cattle were stimulated with the patho...
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Contagious bovine pleuropneumonia (CBPP) is an important disease of cattle in Africa caused by Mycoplasma mycoides subsp. mycoides biotype small colony (MmmSC) and characterized by extensive lesions of pleurisy and pneumonia (13). Among infectious diseases that threaten African cattle, its importance is only second to rinderpest (RP) and, as more and more countries declare being free of RP, CBP...
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Monoclonal antibody (MAb) PK-2 inhibited the in vitro growth of nine Mycoplasma mycoides subsp. mycoides small-colony strains. In contrast to the results with polyclonal antisera, growth inhibition by MAb PK-2 was specific for M. mycoides subsp. mycoides small-colony strains and constituted a reliable means of distinguishing them from other mycoplasmas.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 49 12 شماره
صفحات -
تاریخ انتشار 2005